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Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite <i>Schistosoma mansoni</i>

2020-05-03

Abstract excerpt

At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni . There is a pressing need to develop a reliable functional toolkit to translate these data into new biological insights and targets for intervention. CRISPR-Cas9 was recently demonstra...

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Literature Corpus work
fe63e70e-aea9-532d-aa36-3c9092105368
DOI
10.1101/2020.05.03.074831
Open publication

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Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite <i>Schistosoma mansoni</i>DOI 10.1101/2020.05.03.074831
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