Article

Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni

2021-01-20

Abstract excerpt

<h4>Background: </h4> At least 250 million people worldwide suffer from schistosomiasis, caused by Schistosoma worms. Genome sequences for several Schistosoma species are available, including a high-quality annotated reference for Schistosoma mansoni . There is a pressing need to develop a reliable functional toolkit to translate these data into new biological insights and targets for intervention. CRISPR-Cas9 was...

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Literature Corpus work: af668918-3ac1-5274-a6df-4d687cd0846d
DOI: 10.12688/wellcomeopenres.16031.2

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