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CRISPR-assisted test for Schistosoma haematobium

27 Mar 2023

Abstract excerpt

Schistosomiasis is a major neglected tropical disease targeted for elimination as a public health issue by 2030, however there is an urgent need for more sensitive and specific diagnostic tests suitable to resource-limited settings. Here we developed CATSH, a CRISPR-assisted diagnostic test for Schistosoma haematobium, utilising recombinase polymerase amplification, Cas12a-targeted cleavage and portable real-time...

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PMID: 36973334
DOI: 10.1038/s41598-023-31238-y

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