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Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, <i>Schistosoma mansoni</i>

2022-09-02

Abstract excerpt

<h4>Summary</h4> The identification and characterization of genomic safe harbor sites (GSH) aims to facilitate consistent transgene activity without disruption to the host cell genome. We combined genome annotation and chromatin structure analysis by computational approach to predict the location of four GSHs in the human blood fluke, Schistosoma mansoni , a major infectious pathogen of the tropics. Introduction...

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Literature Corpus work
b2d33332-5f00-5fa9-a887-cd155edbba42
DOI
10.1101/2022.09.02.506379
Open publication

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