Methodology

Scientific method.

A research question is tested against traceable sources. Uncertainty remains explicit, and conclusions remain open to correction.

Ask a precise question

Search with natural language or an exact PMID, DOI, PMCID, gene, variant, phenotype, or OMIM identifier. A precise question narrows the search. It does not predetermine the answer.

Retrieve the literature

Noodle sends the question through its server boundary to the Helena Literature Corpus. Literature Mining owns publication identity, source convergence, deduplication, semantic retrieval, ranking, and cursor continuity. Noodle preserves the returned order as more results load.

Read the source

Open the publication, inspect its source receipt, and judge the study on its methods, population, results, and limitations. Semantic similarity explains why a record appeared in the search. It does not measure evidence strength, causality, or clinical confidence.

Check identity and provenance

Noodle links an entity only when the source projection supplies a normalized identity or an exact supported identifier. Unresolved text stays plain. Gene and variant mentions remain source-indexed mentions unless a governed relationship supplies stronger evidence.

Revise the conclusion

Source-reported corrections and retractions remain visible. A materially changed prepared record receives a new version. Scientific conclusions should change when the underlying evidence changes.