Article

Genetic Predisposition to Hippocampal Atrophy and Risk of Amnestic Mild Cognitive Impairment and Alzheimer’s Dementia

2024-10-22

Abstract excerpt

<h4>Background: </h4> There is paucity of evidence on the association of genetic propensity for hippocampal atrophy with cognitive outcomes. Therefore, we examined the relationship of a Polygenic Risk Score for hippocampal atrophy (PRShp) with the incidence of amnestic mild cognitive impairment (aMCI) and Alzheimer’s disease (AD) as well as the rates of cognitive decline. <h4>Methods:</h4> Participants were drawn...

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Literature Corpus work: fd0f3301-e7ef-5f12-b66a-d89e5c49cb0e
DOI: 10.20944/preprints202410.1707.v1

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