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Genetic risk for Alzheimer’s disease predicts hippocampal volume through the lifespan

2019-07-23

Abstract excerpt

<h4>INTRODUCTION</h4> It is unknown whether genetic risk for Alzheimer’s disease (AD) represents a stable influence on the brain from early in life, or whether effects are age-dependent. It is critical to characterize the effects of genetic risk factors on the primary neural substrate of AD, the hippocampus, throughout life. <h4>METHODS</h4> Relations of polygenic risk score (PGS) for AD, including variants in A...

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Literature Corpus work
f6129474-ba97-5060-a37a-a34e00444ab3
DOI
10.1101/711689
Open publication

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