Article

Polygenic Risk Scores for Alzheimer’s Disease and Mild Cognitive Impairment in Hispanics/Latinos in the U.S: The Study of Latinos – Investigation of Neurocognitive Aging

2021-01-09

Abstract excerpt

<h4>Introduction</h4> Polygenic Risk Score (PRS) are powerful summaries of genetic risk alleles that can potentially be used to predict disease outcomes and guide treatment decisions. Hispanics/Latinos suffer from higher rates of Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) compared to non-Hispanic Whites, yet the strongest known genetic risk factor for AD, APOE - ϵ 4 allele, has weak association w...

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Literature Corpus work: 11720440-362b-5f4b-a80e-bbea88adc49a
DOI: 10.1101/2021.01.08.21249413

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