Article

The human Y and inactive X chromosomes similarly modulate autosomal gene expression

2023-06-07

Abstract excerpt

<h4>SUMMARY</h4> Somatic cells of human males and females have 45 chromosomes in common, including the “active” X chromosome. In males the 46 th chromosome is a Y; in females it is an “inactive” X (Xi). Through linear modeling of autosomal gene expression in cells from individuals with zero to three Xi and zero to four Y chromosomes, we found that Xi and Y impact autosomal expression broadly and with remarkably...

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Literature Corpus work: fc30a4a9-4131-5f53-a259-bd4f46fcb103
DOI: 10.1101/2023.06.05.543763

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