Article

Mechanistic diversification of <i>XIST</i> regulatory network in mammals

2019-07-04

Abstract excerpt

<h4>SUMMARY</h4> X chromosome inactivation (XCI) is a developmental regulatory process that initiates with remarkable diversity in various mammalian species. Here we addressed the contribution of XCI regulators, most of which are lncRNA genes characterized in the mouse, to this mechanistic diversity. By combining analysis of single-cell RNA-seq data from early human embryogenesis with various functional assays in...

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Literature Corpus work: f3e609da-341e-56e8-900f-70ea1068d389
DOI: 10.1101/689430

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