Article

Embryonic loss of human females with partial trisomy 19 identifies region critical for the single active X

2017-03-22

Abstract excerpt

To compensate for the sex difference in the number of X chromosomes, human females, like human males have only one active X. The other X chromosomes in cells of both sexes are silenced in utero by XIST , the Inactive X Specific Transcript gene , that is present on all X chromosomes. To investigate the means by which the human active X is protected from silencing by XIST , we updated the search for a key dosage...

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Literature Corpus work: 632c9335-f27e-52ee-802f-b2ab4339c653
DOI: 10.1101/119495

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