Article

Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies <i>MCM10</i> as a novel regulator of the replication program

2021-09-09

Abstract excerpt

Cellular proliferation depends on the accurate and timely replication of the genome. Several genetic diseases are caused by mutations in key DNA replication genes; however, it remains unclear whether these genes influence the normal program of DNA replication timing. Similarly, the factors that regulate DNA replication dynamics are poorly understood. To systematically identify trans -acting modulators of replicat...

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Literature Corpus work: fbb695a9-f4ae-584c-bfca-3a154733a488
DOI: 10.1101/2021.09.08.459433

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Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies <i>MCM10</i> as a novel regulator of the replication programDOI 10.1101/2021.09.08.459433Read

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