Article

Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression

2024-07-23

Abstract excerpt

Xist, a pivotal player in X chromosome inactivation (XCI), has long been perceived as a cis-acting long noncoding RNA that binds exclusively to the inactive X chromosome (Xi). However, Xists ability to diffuse under select circumstances has also been documented, leading us to suspect that Xist RNA may have targets and functions beyond the Xi. Here, using female mouse embryonic stem cells (ES) and mouse embryonic f...

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Literature Corpus work: f3c0b0f6-d0bd-5eb8-beff-4bf31ae46fac
DOI: 10.1101/2024.07.23.604772

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