Article

Extensive remodelling of <i>XIST</i> regulatory networks during primate evolution

2023-12-04

Abstract excerpt

Unravelling how gene regulatory networks are remodelled during evolution is crucial to understand how species adapt to environmental changes. We addressed this question for X-chromosome inactivation, a process essential to female development that is governed, in eutherians, by the XIST lncRNA and its cis -regulators. To reach high resolution, we studied closely related primate species, spanning 55 million years...

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Literature Corpus work: af2bd1bd-fb6c-5b64-a436-a53430efa387
DOI: 10.1101/2023.12.04.569904

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