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Article

Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation.

Molecular and cellular biology - 1 Oct 2006

Savarese Fabio, Flahndorfer Katja, Jaenisch Rudolf, Busslinger Meinrad, Wutz Anton

Abstract excerpt

Xist is the trigger for X inactivation in female mammals. The long noncoding Xist RNA localizes along one of the two female X chromosomes and initiates chromosome-wide silencing in the early embryo. In differentiated cells, Xist becomes dispensable for the maintenance of the inactive X, and its function for initiation of silencing is lost. How Xist mediates gene repression remains an open question. Here, we use...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16980619
DOI: 10.1128/MCB.00810-06
PMCID: PMC1592878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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