Article

KAS-ATAC reveals the genome-wide single-stranded accessible chromatin landscape of the human genome

2024-05-07

Abstract excerpt

Gene regulation in most eukaryotes involves two fundamental physical processes – alterations in the packaging of the genome by nucleosomes, with active cis -regulatory elements (CREs) generally characterized by an open-chromatin configuration, and the activation of transcription. Mapping these physical properties and biochemical activities genome-wide – through profiling chromatin accessibility and active transcr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eed3ccbc-a330-5ad9-b414-3f8fabda5c77
DOI: 10.1101/2024.05.06.591268

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

KAS-ATAC reveals the genome-wide single-stranded accessible chromatin landscape of the human genomeDOI 10.1101/2024.05.06.591268Read

Identifying transcription factor-bound activators and silencers in the chromatin accessible human genome using ATAC-STARR-seqSemantic proximity Read

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regionsSemantic proximity Read

MOCHA: advanced statistical modeling of scATAC-seq data enables functional genomic inference in large human disease cohortsSemantic proximity Read

Genetic determinants of chromatin accessibility in T cell activation across humansSemantic proximity Read

ShinyArchR.UiO: User-friendly, integrative and open-source tool for visualisation of single-cell ATAC-seq data using ArchRSemantic proximity Read

Index and biological spectrum of accessible DNA elements in the human genomeSemantic proximity Read

Multi-omics analysis of chromatin accessibility and interactions with transcriptome by HiCARSemantic proximity Read

The human transcription factor occupancy landscape viewed using high-resolution in situ base-conversion strand-specific single-molecule chromatin accessibility mappingSemantic proximity Read

maxATAC: genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networksSemantic proximity Read

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells.Semantic proximity Read

Global reference mapping and dynamics of human transcription factor footprintsSemantic proximity Read

An expansive human regulatory lexicon encoded in transcription factor footprints.Semantic proximity Read