Article

maxATAC: genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks

2022-01-29

Abstract excerpt

Transcription factors read the genome, fundamentally connecting DNA sequence to gene expression across diverse cell types. Determining how, where, and when TFs bind chromatin will advance our understanding of gene regulatory networks and cellular behavior. The 2017 ENCODE-DREAM in vivo Transcription-Factor Binding Site ( TFBS ) Prediction Challenge highlighted the value of chromatin accessibility data to TFBS pr...

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Literature Corpus work: bdde6e32-8b54-5fbc-b16e-1d4656e41d5c
DOI: 10.1101/2022.01.28.478235

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