Article

Multi-omics analysis of chromatin accessibility and interactions with transcriptome by HiCAR

2020-11-04

Abstract excerpt

The long-range interactions of cis-regulatory elements (cREs) play a central role in regulating the spatial-temporal gene expression program of multi-cellular organism. cREs are characterized by the presence of accessible (or open) chromatin, which can be identified at genome-wide scale with assays such as ATAC-seq, DHS-seq, and FAIRE-seq. However, it remains technically challenging to comprehensively identify the...

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Literature Corpus work: 7952fe60-79cc-540a-8062-05b1ac397788
DOI: 10.1101/2020.11.02.366062

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