Article

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

2015-03-17

Abstract excerpt

Transcription factors canonically bind nucleosome-free DNA, making the positioning of nucleosomes within regulatory regions crucial to the regulation of gene expression. We observe a highly structured pattern of DNA fragment lengths and positions generated by the assay of transposase accessible chromatin (ATAC-seq) around nucleosomes in S. cerevisiae , and use this distinctive two-dimensional nucleosomal “fingerp...

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Literature Corpus work: 6af6efc5-f8e0-5aa7-9019-a352faefc975
DOI: 10.1101/016642

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