Article

Identifying transcription factor-bound activators and silencers in the chromatin accessible human genome using ATAC-STARR-seq

2022-03-28

Abstract excerpt

<h4>ABSTRACT</h4> Massively parallel reporter assays test the capacity of putative gene regulatory elements to drive transcription on a genome-wide scale. Most gene regulatory activity occurs within accessible chromatin, and recently described methods have combined assays that capture these regions—such as assay for transposase-accessible chromatin using sequencing (ATAC-seq)—with self-transcribing active regulat...

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Literature Corpus work: 1df884a9-0f06-5368-9c35-c4352565a5af
DOI: 10.1101/2022.03.25.485870

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