Article

Index and biological spectrum of accessible DNA elements in the human genome

2019-10-29

Abstract excerpt

DNase I hypersensitive sites (DHSs) are generic markers of regulatory DNA and harbor disease- and phenotypic trait-associated genetic variation. We established high-precision maps of DNase I hypersensitive sites from 733 human biosamples encompassing 439 cell and tissue types and states, and integrated these to precisely delineate and numerically index ~3.6 million DHSs encoded within the human genome, providing a...

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Literature Corpus work: f330d6ab-15de-5567-9e53-a25e72368934
DOI: 10.1101/822510

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