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Article

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells.

Scientific reports - 1 Jun 2016

Scharer Christopher D, Blalock Emily L, Barwick Benjamin G, Haines Robert R, Wei Chungwen, Sanz Ignacio, Boss Jeremy M

Abstract excerpt

Biobanking is a widespread practice for storing biological samples for future studies ranging from genotyping to RNA analysis. However, methods that probe the status of the epigenome are lacking. Here, the framework for applying the Assay for Transposase Accessible Sequencing (ATAC-seq) to biobanked specimens is described and was used to examine the accessibility landscape of naïve B cells from Systemic Lupus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27249108
DOI: 10.1038/srep27030
PMCID: PMC4888756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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