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The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in the <i>C. elegans</i> germ line

2024-09-01

Abstract excerpt

Mitotic spindle orientation sets the cell division plane and is thus critical for maintaining tissue organization. The C. elegans gonad is tube-shaped, with germ cells forming a circumferential monolayer around a shared inner core of cytoplasm called the rachis. Each germ cell is connected to the rachis via a stable cytoplasmic bridge, polarizing germ cells along their rachis-basal axis. How this tissue organizat...

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Literature Corpus work
ec9bbeb0-e5e3-5f9f-a546-ac8f75f94f5a
DOI
10.1101/2024.08.31.610619
Open publication

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The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in the <i>C. elegans</i> germ lineDOI 10.1101/2024.08.31.610619
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