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Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

2020-11-09

Abstract excerpt

Non-additive genetic variance for complex traits is traditionally estimated from data on relatives. It is notoriously difficult to estimate without bias in non-laboratory species, including humans, because of possible confounding with environmental covariance among relatives. In principle, non-additive variance attributable to common DNA variants can be estimated from a random sample of unrelated individuals with...

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Literature Corpus work
eb030247-49cd-5dec-83d5-140c88f968b3
DOI
10.1101/2020.11.09.375501
Open publication

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Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individualsDOI 10.1101/2020.11.09.375501
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