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Article

Data and theory point to mainly additive genetic variance for complex traits.

PLoS genetics - 29 Feb 2008

Hill William G, Goddard Michael E, Visscher Peter M

Abstract excerpt

The relative proportion of additive and non-additive variation for complex traits is important in evolutionary biology, medicine, and agriculture. We address a long-standing controversy and paradox about the contribution of non-additive genetic variation, namely that knowledge about biological pathways and gene networks imply that epistasis is important. Yet empirical data across a range of traits and species...

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Identifiers

PMID: 18454194
DOI: 10.1371/journal.pgen.1000008
PMCID: PMC2265475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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