Article
Narrow-sense heritability estimation of complex traits using identity-by-descent information.
Heredity - 1 Dec 2018
Evans Luke M, Tahmasbi Rasool, Jones Matt, Vrieze Scott I, Abecasis Gonçalo R, Das Sayantan, Bjelland Douglas W, de Candia Teresa R, Yang Jian, Goddard Michael E, Visscher Peter M, Keller Matthew C
Abstract excerpt
Heritability is a fundamental parameter in genetics. Traditional estimates based on family or twin studies can be biased due to shared environmental or non-additive genetic variance. Alternatively, those based on genotyped or imputed variants typically underestimate narrow-sense heritability contributed by rare or otherwise poorly tagged causal variants. Identical-by-descent (IBD) segments of the genome share all...
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