Article

Profiling tyrosine kinase substrate recognition using bacterial peptide display and deep sequencing

2025-12-30

Abstract excerpt

Tyrosine kinases control a wide range of cell signaling pathways that are central to human physiology, and they are dysregulated in a variety of human diseases, most notably cancers. Our understanding of tyrosine kinase biology hinges upon a clear delineation of their protein substrates. Thus, much effort has been invested into defining the substrate specificities of tyrosine kinases, which is partly driven by rec...

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Literature Corpus work: eabe3b8b-3e31-5516-8e3c-e3be1c454b2d
DOI: 10.64898/2025.12.28.696772

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