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Article

Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model

2023-09-27

Abstract excerpt

Abnormal cellular and circuit excitability is believed to drive many core phenotypes in fragile X syndrome (FXS). The dentate gyrus is a brain area performing critical computations essential for learning and memory. However, little is known about dentate circuit defects and their mechanisms in FXS. Understanding dentate circuit dysfunction in FXS has been complicated by the presence of two types of excitatory neur...

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Literature Corpus work
e9c100ed-54f0-5b12-b1a0-229a4a7113e5
DOI
10.1101/2023.09.27.559792
Open publication

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Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelDOI 10.1101/2023.09.27.559792
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