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Higher hyperpolarization activated current (I <sub>h</sub> ) in a subpopulation of interneurons in stratum oriens of area CA1 in the hippocampus of Fragile X mice

2022-12-21

Abstract excerpt

Fragile X syndrome is the most common inherited form of intellectual disability and the leading monogenetic cause of autism. Studies in mouse models of autism spectrum disorders, including the Fmr1 knockout (FX) mouse, suggest that abnormal inhibition in hippocampal circuits contributes to behavioral phenotypes. We and others previously identified changes in multiple voltage-gated ion channels in hippocampal excit...

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Literature Corpus work
d64a03f5-704f-582a-8c3c-9a4f5389e2dd
DOI
10.1101/2022.12.20.521268
Open publication

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Higher hyperpolarization activated current (I <sub>h</sub> ) in a subpopulation of interneurons in stratum oriens of area CA1 in the hippocampus of Fragile X miceDOI 10.1101/2022.12.20.521268
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