Article

Aberrant hippocampal gamma oscillations in a mouse model of Fragile X Syndrome: Insights from in vitro slice models

2025-06-16

Abstract excerpt

<title>Abstract</title> Background Fragile X syndrome (FXS) is the most common inherited intellectual disability, caused by the loss of fragile X mental retardation protein (FMRP), which regulates neuronal signaling and plasticity. FXS patients and <italic>Fmr1</italic> knockout (KO) mice exhibit sensory hypersensitivity, hyperarousal, and hippocampus-dependent learning deficits. Dysregulated metabotropic...

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Literature Corpus work: a348a028-8246-5c21-8ccf-184a72af96c9
DOI: 10.21203/rs.3.rs-6800147/v1

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