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Hyperexcitability in the olfactory bulb and impaired fine odor discrimination in the <i>Fmr1</i> KO mouse model of fragile X syndrome

2023-04-10

Abstract excerpt

Fragile X syndrome (FXS) is the single most common monogenetic cause of autism spectrum disorders in humans. FXS is caused by loss of expression of the Fragile X mental retardation protein (FMRP), an mRNA-binding protein encoded on the X chromosome involved in suppressing protein translation. Sensory processing deficits have been a major focus of studies of FXS in both humans and rodent models of FXS, but olfactor...

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Literature Corpus work
e2de7f75-9011-530c-ab9e-5c1cdf745c4c
DOI
10.1101/2023.04.10.536251
Open publication

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Hyperexcitability in the olfactory bulb and impaired fine odor discrimination in the <i>Fmr1</i> KO mouse model of fragile X syndromeDOI 10.1101/2023.04.10.536251
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