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Article

Physiological and morphological characterization of dentate granule cells in the p35 knock-out mouse hippocampus: evidence for an epileptic circuit.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 13 Oct 2004

Patel Leena S, Wenzel H Jürgen, Schwartzkroin Philip A

Abstract excerpt

There is a high correlation between pediatric epilepsies and neuronal migration disorders. What remains unclear is whether there are intrinsic features of the individual dysplastic cells that give rise to heightened seizure susceptibility, or whether these dysplastic cells contribute to seizure activity by establishing abnormal circuits that alter the balance of inhibition and excitation. Mice lacking a...

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Identifiers

PMID: 15483119
DOI: 10.1523/JNEUROSCI.2943-04.2004
PMCID: PMC6730067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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