Article

Single-cell and neuronal network alterations in an <i>in vitro</i> model of Fragile X syndrome

2018-07-10

Abstract excerpt

The Fragile X mental retardation protein (FMRP) is involved in many cellular processes and it regulates synaptic and network development in neurons. Its absence is known to lead to intellectual disability, with a wide range of co-morbidities including autism. Over the past decades, FMRP research focused on abnormalities both in glutamatergic and GABAergic signalling, and an altered balance between excitation and i...

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Literature Corpus work: b43047a7-1215-56dc-90b5-ff0e15d89f3b
DOI: 10.1101/366997

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