Article
Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring
2021-06-28
Abstract excerpt
A surprising and well-replicated result in genetic studies of human longevity is that centenarians appear to carry disease-associated variants in numbers similar to the general population. With the proliferation of large genome-wide association studies (GWAS) in recent years, investigators have turned to polygenic scores to leverage GWAS results into a measure of genetic risk that can better predict risk of diseas...
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Identifiers and source
- Literature Corpus work
- e9bd4cf4-9538-5539-9048-48ed26b23fdd
- DOI
- 10.1101/2021.06.23.21257874