Population Pharmacokinetics of Isoniazid: A Systemic Review

Abstract excerpt

<h4>Background: </h4> Isoniazid (INH) is one of the drugs in the classical therapy for pulmonary tuberculosis. Several INH population pharmacokinetic models were established in the last ten years. This systemic review was performed i) to summarize published population pharmacokinetic (PPK) models of INH and ii) to summarize and explore identified covariates influencing the INH pharmacokinetic models. Methods. A se...

Topics

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• Antitubercular Agents
• Area Under Curve
• Arylamine N-Acetyltransferase
• Child
• Computer Simulation
• Genotype
• Isoniazid
• Phenotype

Identifiers and source

Literature Corpus work

dad2af78-c6cb-51a9-ba9b-befeba68907a

DOI

10.22541/au.170670480.06205240/v1