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Article

Parametric population pharmacokinetics of isoniazid: a systematic review.

Expert review of clinical pharmacology - 1 May 2023

Li Jinmeng, Cai Xinjun, Chen Yueting, Wang Chenyu, Jiao Zheng

Abstract excerpt

INTRODUCTION: Isoniazid (INH) plays an important role in prevention and treatment of tuberculosis (TB). However, large pharmacokinetic (PK) variations are observed in patients receiving standard INH dosages. Considering the influence of PK variations on INH efficacy or adverse reactions, we reviewed the population PK studies of INH and explored significant covariates that influence INH PK. METHODS: The PubMed and...

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Identifiers

PMID: 36971782
DOI: 10.1080/17512433.2023.2196401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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