Article
Model-based precision dosing and remedial dosing recommendations for delayed or missed doses of isoniazid in Chinese patients with tuberculosis
2023-09-11
Abstract excerpt
<h4>Aim: </h4> Isoniazid (INH) has been used as a first-line drug to treat tuberculosis (TB) for more than 50 years. However, large inter-individual variability was found in its pharmacokinetics, and how to handle a delayed or missed dose of INH remains unclear. This study aimed to develop a population pharmacokinetics (PPK) model of INH in Chinese patients with TB to provide model-informed precision dosing and ex...
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Identifiers and source
- Literature Corpus work
- 6da4be49-2880-584f-b5ed-86368e55956c
- DOI
- 10.22541/au.169445732.29689359/v1