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Global Estimates and Determinants of Antituberculosis Drug Pharmacokinetics in Children and Adolescents: A Systematic Review and Individual Patient Data Meta-Analysis

2022-07-13

Abstract excerpt

Background: Suboptimal exposure to antituberculosis drugs has been associated with unfavourable treatment outcomes in children and adolescents. We investigated estimates and determinants of first-line antituberculosis drug pharmacokinetics in children and adolescents at a global level. <br><br>Methods: In this systematic review and individual patient data meta-analysis, we searched MEDLINE, Embase, and Web of Scie...

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Literature Corpus work
5d9a81a6-bfd3-5c45-9deb-85eac627e45a
DOI
10.2139/ssrn.4161712
Open publication

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Global Estimates and Determinants of Antituberculosis Drug Pharmacokinetics in Children and Adolescents: A Systematic Review and Individual Patient Data Meta-AnalysisDOI 10.2139/ssrn.4161712
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