Article

iPSC-Derived Microglia-like Cells Exhibit Protocol-Dependent Transcriptomic Features and Robust Phagocytosis of Glioma Cells

2026-07-22

Abstract excerpt

<h4>Summary</h4> Microglia are the brain-resident macrophages and key regulators of the brain tumor microenvironment. Although induced pluripotent stem cell-derived microglia (iMG) provide a valuable model for studying human microglial, systematic comparisons of differentiation protocols are limited, and their utility for modeling microglia-tumor cell interactions remains underexplored. Here, we analyzed 54 publi...

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Literature Corpus work: d8f699e3-8a5c-5cc2-8208-258955c52cde
DOI: 10.64898/2026.07.21.739939

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