Article

Long-term co-maturation of stem cell-derived microglia and neuronal networks: an optimized platform to assess human microglial contribution to neuronal function

2025-10-24

Abstract excerpt

Microglia-neuron interactions play a central role in a variety of central nervous system disorders. Technologies using human induced pluripotent stem cells (hiPSCs) have been developed to model human brain cells with the goal to understand their function. To effectively study neuro-immune crosstalk and investigate microglial contributions to neuronal network development and function, both microglia and neurons sho...

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Literature Corpus work: d0d54412-86a0-57ee-9900-4eb78a6c7a40
DOI: 10.1101/2025.10.24.684345

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