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Article

Defined human tri-lineage brain microtissues

2025-08-07

Abstract excerpt

<h4>SUMMARY</h4> Microglia are the immune cells of the central nervous system and are thought to be key players in both physiological and disease conditions. Several microglial features are poorly conserved between mice and human, such as the function of the neurodegeneration-associated immune receptor Trem2. Induced pluripotent stem cell (iPSC)-derived microglia offer a powerful opportunity to generate and study...

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Literature Corpus work
8c6f76f6-4dad-582b-91e1-36d98ccd6888
DOI
10.1101/2025.08.05.668605
Open publication

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Defined human tri-lineage brain microtissuesDOI 10.1101/2025.08.05.668605
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