Article
Transcriptional benchmarking of human monocyte-derived microglia-like cells and iPSC-derived microglia reveals distinct immune-alert and homeostatic programmes
2026-07-28
Abstract excerpt
<title>Abstract</title> <p> Human microglia play central roles in brain homeostasis, immune surveillance and neurodegeneration, yet <italic>in vitro</italic> human microglial models differ widely in cellular origin and culture context, complicating interpretation and translational application. Here, we systematically compare transcriptional and functional states across primary monocytes, monocyte-derived macro...
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Identifiers and source
- Literature Corpus work
- 125f4084-8875-5160-a7e5-87ad248dfac4
- DOI
- 10.21203/rs.3.rs-10477073/v1