Article

Comprehensive identification of coronary artery disease-associated variants regulating vascular smooth muscle cell gene expression

2024-10-09

Abstract excerpt

Coronary artery disease (CAD) is a complex disorder with genetic and environmental influences. Genome-wide association studies (GWAS) have identified over 300 genomic loci associated with disease risk. However, identifying the functional variants within these loci has been limited in large part due to linkage disequilibrium. This represents a critical step in understanding the molecular mechanisms underlying disea...

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Literature Corpus work: d8a36408-3deb-5c9d-82e3-4d5d2681edca
DOI: 10.1101/2024.10.07.617126

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