Article

Single cell variant to enhancer to gene map for coronary artery disease

2024-11-13

Abstract excerpt

Although genome wide association studies (GWAS) in large populations have identified hundreds of variants associated with common diseases such as coronary artery disease (CAD), most disease-associated variants lie within non-coding regions of the genome, rendering it difficult to determine the downstream causal gene and cell type. Here, we performed paired single nucleus gene expression and chromatin accessibility...

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Literature Corpus work: fbc83b8e-84b4-5cdd-8381-6b587b758167
DOI: 10.1101/2024.11.13.24317257

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