Article

Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci

2025-02-21

Abstract excerpt

Coronary artery disease (CAD) is the leading cause of death worldwide. Recently, hundreds of genomic loci have been shown to increase CAD risk, however, the molecular mechanisms underlying signals from CAD risk loci remain largely unclear. We sought to pinpoint the candidate causal coding and non-coding genes of CAD risk loci in a cell type-specific fashion. We integrated the latest statistics of CAD genetics from...

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Literature Corpus work: 3e772125-d3bb-55bf-8499-d6b9100b1bda
DOI: 10.1101/2025.02.20.639228

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