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<i>In silico</i> tools for accurate HLA and KIR inference from clinical sequencing data empower immunogenetics on individual-patient and population scales

2020-04-25

Abstract excerpt

Immunogenetic variation in humans is important in research, clinical diagnosis and increasingly a target for therapeutic intervention. Two highly polymorphic loci play critical roles, namely the human leukocyte antigen (HLA) system, which is the human version of the major histocompatibility complex (MHC), and the Killer-cell immunoglobulin-like receptors (KIR) that are relevant for responses of Natural Killer (NK)...

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Literature Corpus work
d3c33a78-6999-5155-be18-befbf9478a0f
DOI
10.1101/2020.04.24.060459
Open publication

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<i>In silico</i> tools for accurate HLA and KIR inference from clinical sequencing data empower immunogenetics on individual-patient and population scalesDOI 10.1101/2020.04.24.060459
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