Article
High-resolution human KIR genotyping.
Immunogenetics - 1 Aug 2022
Downing Jonathan, D'Orsogna Lloyd
Abstract excerpt
Killer immunoglobulin-like receptors (KIR) regulate the function of natural killer cells through interactions with various ligands on the surface of cells, thereby determining whether natural killer (NK) cells are to be activated or inhibited from killing the cell being interrogated. The genes encoding these proteins display extensive variation through variable gene content, copy number and allele polymorphism....
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