Article

Benchmark of tools for <i>in silico</i> prediction of MHC class I and class II genotypes from NGS data

2022-04-29

Abstract excerpt

The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentability of tumour antigens to the immune system. While knowledge of these genotypes is of utmost importance to study differences in immune responses between cancer patients, gold standard, PCR-derived genotypes are...

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Literature Corpus work: 89b5a9dc-b731-55b8-88b4-a3c3641d8d49
DOI: 10.1101/2022.04.28.489842

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