Article
Evaluation of computational programs to predict HLA genotypes from genomic sequencing data.
Briefings in bioinformatics - 1 Mar 2018
Bauer Denis C, Zadoorian Armella, Wilson Laurence O W, Thorne Natalie P
Abstract excerpt
Motivation: Despite being essential for numerous clinical and research applications, high-resolution human leukocyte antigen (HLA) typing remains challenging and laboratory tests are also time-consuming and labour intensive. With next-generation sequencing data becoming widely accessible, on-demand in silico HLA typing offers an economical and efficient alternative. Results: In this study we evaluate the HLA...
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