Article

T1K: efficient and accurate KIR and HLA genotyping with next-generation sequencing data

2022-10-27

Abstract excerpt

Killer immunoglobulin-like receptor (KIR) genes and human leukocyte antigen (HLA) genes are highly polymorphic in a population and play important roles in innate and adaptive immunity. We have developed a novel computational method T1K that can efficiently and accurately infer the KIR or HLA alleles from next-generation sequencing data. T1K is flexible and is compatible with various sequencing platforms including...

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Literature Corpus work: fddec7d7-4cb2-571b-a2a1-c2e6dce487e6
DOI: 10.1101/2022.10.26.513955

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